Working Paper
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Structure of the microtubule anchoring factor NEDD1 bound to the γ-tubulin ring complex
(2024)bioRxivThe γ-tubulin ring complex (γ-TuRC) is an essential multiprotein assembly, in which γ-tubulin, GCP2-6, actin, MZT1 and MZT2 form an asymmetric cone-shaped structure that provides a template for microtubule nucleation. The γ-TuRC is recruited to microtubule organizing centers (MTOCs), such as centrosomes and pre-existing mitotic spindle microtubules, via the evolutionarily-conserved attachment factor NEDD1. NEDD1 contains an N-terminal ...Working Paper -
Global evidence on the income elasticity of willingness to pay, relative price changes and public natural capital values
(2024)arXivWhile the global economy continues to grow, ecosystem services tend to stagnate or decline. Economic theory has shown how such shifts in relative scarcities can be reflected in project appraisal and accounting, but empirical evidence has been sparse to put theory into practice. To estimate relative price changes in ecosystem services to be used for making such adjustments, we perform a global meta-analysis of contingent valuation studies ...Working Paper -
Maximising the development value of MDB callable capital: Project findings and path forward
(2024)ODI Working PaperCallable capital is a central pillar of the multilateral development bank (MDB) model, but stakeholders lack basic standards to understand its value to operational capacity. The risk of a crisis requiring a capital call is less than 1% in conservative scenarios and the amount needed would be a fraction of the $891 billion currently subscribed. The rules and processes for a capital call are ambiguous and need to be clarified at MDBs and ...Working Paper -
What Makes an MDB an MDB? Southern-led multilateral banks and the sovereign debt crisis
(2025)ODI Global Working PaperA dispute over the preferred creditor status of Afreximbank and Trade and Development Bank has delayed sovereign debt restructuring in Ghana, Malawi and Zambia. The case highlights how the growth of Southern-led multilateral development banks complicates sovereign debt resolution. Whether Southern-led MDBs are exempt from sovereign restructurings has important implications for their financial sustainability and operational strategies. The ...Working Paper -
Southern-led multilateral channels for climate finance
(2025)ODI Global Working PaperMultilateral development banks (MDBs) led by Global South countries are starting to prioritise climate finance and have substantial potential to do more. Southern-led MDBs have deep local knowledge and strong relations with recipient governments but also face technical and financial obstacles to increase their climate investments. Targeted support from external development agencies, legacy MDBs and climate funds to Southern-led MDBs is a ...Working Paper -
Single Cu Atom Sites on Co3O4 Activate Interfacial Oxygen for Enhanced Reactivity and Selective Gas Sensing at Low Temperature
(2025)arXivControlling the redox landscape of transition metal oxides is central to advancing their reactivity for heterogeneous catalysis or high-performance gas sensing. Here we report single Cu atom sites (1.42 wt%) anchored on Co3O4 nanoparticles (Cu1-Co3O4) that dramatically enhance reactivity and molecular sensing properties of the support at low temperature. The Cu1 are identified by X-ray adsorption near edge structure and feature strong ...Working Paper -
Detecting the Critical Thresholds of an Urban Traffic System Using Percolation Theory
(2025)Research SquareWe employ high-resolution speed data to develop a percolation theory-based network analysis framework by integrating two identified critical thresholds. This framework effectively captures the dynamic behaviors of traffic networks before, during, and after the critical phase transition point. Our study reveals characteristic congestion thresholds around this critical phase transition for each studied network. Critical thresholds mark ...Working Paper -
An Edge-Sensing Platform for Predictive Maintenance Application
(2024)Fully functional components are the foundation of any technical system, such as the electric power transmission and distribution grid. To transition from today’s time-based maintenance of these components to an intelligent predictive maintenance strategy, the health condition of all components needs to be known continuously at any instant in time. For this, sensors and monitoring systems have to be pervasively deployed, and IoT-based ...Working Paper -
What drives students’ decision to enroll abroad for tertiary education?
(2025)CES Working Paper SeriesThis study examines the decision-making processes of students considering studying abroad, with a focus on short-term priorities, long-term benefits, practical constraints, and the role of social networks. Using subjective expectation data from Bosnia and Herzegovina, I show that students usually prioritize immediate factors such as social life, parental support, and education quality over long-term outcomes such as job prospects and ...Working Paper -
Third-Party Pricing with Data-Driven Learning
(2025)SSRNFirms such as online retailers are increasingly turning to specialized pricing software companies to perform data analytics and help them optimize their prices. Firms upload their raw data into these companies’ cloud-based platforms, allowing their algorithms to learn from the data and improve their ability to later provide ana lytics to other market participants. We derive the implications of this data-driven learning on the profits of ...Working Paper -
Space for People, Not Cars: A Visual Choice Experiment on Urban Street Redesigns
(2025)OSF PreprintsHow and by whom streets are used has become a politically contested issue as cities face growing pressures from climate change, land scarcity, and social inequalities. Despite the central role of public opinion in implementation success, we lack systematic empirical evidence on how specific street design features shape attitudes. We study public opinion as a prospective evaluation of street redesign and measure acceptance, willingness to ...Working Paper -
Peptide Barcodes for miRNA activity assessment in mammalian cells
(2025)bioRxivStudies of gene regulation require measurements of mRNA and protein levels of a regulated gene. Recently, parallel reporter assays have been introduced to study the regulation of multiple genes at once. While transcriptional regulation can be probed by next generation sequencing, post-transcriptional regulation requires the ability to measure multiple proteins in the same experiment. Multiplexing with the help of fluorescent proteins ...Working Paper -
Climate Change and Poverty Traps: Adopting an Integrated Model Framework
(2025)Economics Working Paper SeriesThis paper develops a tractable North-South framework with overlapping gen erations and endogenous growth dynamics to study poverty traps in the light of climate change. Global pollution is a negative externality of capital accumulation in both world regions, and climate change causes damages to the stock of physical capital in the more vulnerable South. Non-linearities in global pollution dynamics, in the impact and abatement functions ...Working Paper -
Strategic Debt in a Monetary Economy
(2025)KOF Working PapersProducers can leverage their bargaining power vis-à-vis consumers by entering bargaining with debt. We discover novel general-equilibrium effects of such strategic debt by developing a money-search framework featuring heterogeneous consumers. Debt distorts trade along two margins: it destroys matches with low-preference consumers and it tightens liquidity constraints within matches. While the fiscal authority can fully eliminate strategic ...Working Paper -
Antifragile Control Systems
(2023)arXivUrban road traffic continuously evolves under uncertainty. Existing traffic control systems only possess a local perspective over the multiple scales of traffic evolution, namely the intersection level, the corridor level, and the region level respectively. Capturing uncertainty under complex traffic spatio-temporal interactions is a very difficult problem and we often experience how fragile such systems are in reality. But luckily, despite ...Working Paper -
Sequencing carbon dioxide removal into the EU ETS
(2024)CESifo Working PapersNovel Carbon Dioxide Removal (CDR) technologies have seen a first wave of deployment, driven by investments through voluntary carbon markets and by specific support policies. To sustain the momentum, a credible long-term policy path is urgently needed to lead removal technologies through the valley of death, and to ramp-up sufficient capacities to limit global warming to well below 2°C. The integration of removals into carbon compliance ...Working Paper -
Can Paying Employees to Quit Boost Motivation? Evidence from a Lab Experiment
(2025)Center for Law & Economics Working Paper SeriesWe investigate whether pay-to-quit incentives can enhance worker productivity by conducting an online laboratory experiment with 1,000 participants. Subjects were randomly assigned to either a control condition, which offered no financial inducement to quit, or to a treatment condition in which they received a one-time offer of CHF 5 to exit the task. Our findings indicate that participants who reject the quit offer complete, on average, ...Working Paper -
Inclusive street re-design for bicycles and micromobility
(2025)Arbeitsberichte Verkehrs- und RaumplanungAutomobiles account for 30% of Switzerland’s greenhouse gas emissions, prompting a pivot towards sustainable transport. This study examined public sentiment on a research-based vision for cities to transition to an E-Bike City (EBC) – prioritizing sustainable modes by reallocating street space to micromobility. Public perceptions were explored through content analysis of comments from a newspaper article about the EBC initiative, with ...Working Paper -
Mitigating the Judicial Human-AI Fairness Gap
(2025)Center for Law & Economics Working Paper SeriesAre robot judges perceived as less fair than human judges? If so, how can this perceived judicial human-AI fairness gap be mitigated? We conduct a large online experiment with more than 4,800 observations to explore whether delegating judicial tasks to algorithms affects perceived procedural fairness and how human-in-the-loop interventions might offset any fairness gap. Participants are randomly assigned to assess one of the following ...Working Paper -
Spine Detection and Vertebral Body Segmentation in the Pcdare Software with Machine Learning
(2025)SSRNBackground and Objective: Optical 3D scanning is an emerging technology for evaluating back shapes in patients with spinal deformities. Despite the potential of surface scanning to avoid radiation exposure, its reliability and accuracy remain moderate compared to radiography, which is the current gold standard in clinical practice. PCdare is an open-source software that is used to analyze and compare the optical 3D surface scans of the ...Working Paper