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Microarray gene expression profiling of aortic genes of APOE-deficient mice receiving atherosclerosis treatment with the antioxidant vitamin E
(2012)Hypercholesterolemic APOE-deficient mice are a widely used experimental model of atherosclerosis and increased generation of reactive oxygen species (ROS) is a prominent feature of atherosclerosis development. To study the impact of ROS on atherogenesis, we treated APOE-deficient mice for 7 months with the antioxidant vitamin E (2000 IU/kg diet) and performed whole genome microarray gene expression profiling of aortic genes. Microarray ...Dataset -
Microarray gene expression profiling of transgenic mice with myocardium-specific over-expression of fatty acid synthase (FASN)
(2013)The fatty acid synthase (FASN) is the major fat synthesizing enzyme. FASN is an indispensable enzyme because mice with genetic deletion of Fasn are not viable. Apart from its physiological function, previous studies indicated that FASN could also exert a pathophysiological role, in the heart, because patients with heart failure showed up-reguation of FASN. To investigate the in vivo function of FASN up-regulation in the heart, we generated ...Dataset -
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Data collection for the Grimsel In-Situ Stimulation and Circulation (ISC) experiment
(2018)Data Collection -
Halfway Demolition
(2018)An old pyschiatric clinic in Melle, Belgium. Already there since the turn of the twentieth century. Back then, an unique place, ahead of its time. (...) Its excistence, however, had already suffered a first demolition. Yet, by considering this as a chance rather than a loss, an opening came into view. (...) And yet, the building stood there. The building existed. Except from that the building might turn the usual ideas around - might ...Video