Review Article
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Technological and policy options for the defossilisation of chemical manufacturing
(2024)RSC SUSTAINABILITYThe chemical industry plays a pivotal role in modern society, providing essential products like plastics, consumer products, pharmaceuticals, speciality and agricultural chemicals. With increasing global prosperity and evolving societal demands, the need for sustainable chemicals is more pressing than ever. Essentially, the production of chemicals as we know it today is based on the use of fossil fuel for supplying the feedstock needed ...Review Article -
Stromal cells and epigenetics: emerging key players of chronic inflammatory skin diseases
(2024)BMB ReportsEpigenetic alterations play a crucial role in developmental processes, tissue regeneration, and cellular differentiation. Epigenetic changes are dynamically reversible. Various drugs that target DNA methyltransferases or histone deacetylases have demonstrated their ability to restore normal epigenetic patterns in a number of diseases. While the involvement of epigenetic modifications has been identified in chronic inflammatory diseases, ...Review Article -
A framework for understanding collective microbiome metabolism
(2024)Nature MicrobiologyMicrobiome metabolism underlies numerous vital ecosystem functions. Individual microbiome members often perform partial catabolism of substrates or do not express all of the metabolic functions required for growth. Microbiome members can complement each other by exchanging metabolic intermediates and cellular building blocks to achieve a collective metabolism. We currently lack a mechanistic framework to explain why microbiome members ...Review Article -
Toward low-friction and high-adhesion solutions: Emerging strategies for nanofibrous scaffolds in articular cartilage engineering
(2025)Biomaterials AdvancesAging, trauma, pathology, and poor natural tissue regeneration are the leading causes of osteoarthritis (OA), an articular cartilage disease. Electrospun scaffolds have gained attention as potential matrices for the treatment of OA because of their high degree of ECM mimicry, which suits chondrocyte migration, adhesion, and proliferation. However, none of the products recently introduced in the market are nanofiber-based. This study aimed ...Review Article -
Working fluid and system optimisation of organic Rankine cycles via computer-aided molecular design: A review
(2025)Progress in Energy and Combustion ScienceOrganic Rankine cycle (ORC) systems are a class of distributed power-generation systems that are suitable for the efficient conversion of low-to-medium temperature thermal energy to useful power. These versatile systems have significant potential to contribute in diverse ways to future clean and sustainable energy systems through, e.g., deployment for waste-heat recovery in industrial facilities, but also the utilisation of renewable-heat ...Review Article -
Methods and computational tools to study eukaryotic cell migration in vitro
(2024)Frontiers in Cell and Developmental BiologyCellular movement is essential for many vital biological functions where it plays a pivotal role both at the single cell level, such as during division or differentiation, and at the macroscopic level within tissues, where coordinated migration is crucial for proper morphogenesis. It also has an impact on various pathological processes, one for all, cancer spreading. Cell migration is a complex phenomenon and diverse experimental methods ...Review Article -
A review on artificial intelligence applications for facades
(2025)Building and EnvironmentThis review applies a transformer-based topic model to reveal trends and relationships in Artificial Intelligence (AI)-driven facade research, with a focus on architectural, environmental, and structural aspects. AI methods reviewed include Machine Learning (ML), Deep Learning (DL), and Computer Vision (CV). Overall, a significantly growing interest in applying AI methods can be observed across all research areas. However, noticeable ...Review Article -
Trends in Photopolymerization 3D Printing for Advanced Drug Delivery Applications
(2024)BiomacromoleculesSince its invention in the 1980s, photopolymerization-based 3D printing has attracted significant attention for its capability to fabricate complex microstructures with high precision, by leveraging light patterning to initiate polymerization and cross-linking in liquid resin materials. Such precision makes it particularly suitable for biomedical applications, in particular, advanced and customized drug delivery systems. This review ...Review Article -
Structure Prediction and Computational Protein Design for Efficient Biocatalysts and Bioactive Proteins
(2024)Angewandte Chemie. International EditionThe ability to predict and design protein structures has led to numerous applications in medicine, diagnostics and sustainable chemical manufacture. In addition, the wealth of predicted protein structures has advanced our understanding of how life's molecules function and interact. Honouring the work that has fundamentally changed the way scientists research and engineer proteins, the Nobel Prize in Chemistry in 2024 was awarded to David ...Review Article -
The Russian invasion of Ukraine and changes in MEPs' conceptions of security
(2024)International PoliticsOptions of organizing security are often determined by how it is conceived. The paper focuses on how European security has been discussed in the European Parliament in response to the Russian annexation of Crimea in 2014 and the Russian invasion of Ukraine in 2022. Drawing on parliamentary debates and meaning-making of security, we construct a threefold argument. Firstly, when MEPs discuss whose security needs to be addressed, we observe ...Review Article -
Exploring Niobium oxide-based materials for fast-charging lithium-ion anodes: Insights from structure to property
(2025)Materials Science and Engineering R: ReportsThe concomitant environmental issues related to the consumption of fossil fuels underscore the significance of accelerating the global electrification. However, the shift towards electrification increases the demands for greater energy density, charging speeds, and safety in electrical energy storage systems such as lithium-ion batteries (LIBs). In pursuit of this goal, one branch of LIBs’ anode research has focused on niobium oxide-based ...Review Article -
Potential Role of Photochemistry in Environmental DNA Degradation
(2024)Environmental Science & Technology LettersGiven the severe loss of species richness across diverse ecosystems, there is an urgent need to assess and monitor biodiversity on a global scale. The analysis of environmental DNA (eDNA), referring to any DNA extracted from environmental samples and subsequently sequenced, is a promising method for performing such biodiversity related studies. However, a comprehensive understanding of the factors that drive distinct eDNA degradation rates ...Review Article -
Microbial melatonin metabolism in the human intestine as a therapeutic target for dysbiosis and rhythm disorders
(2024)npj Biofilms and MicrobiomesMelatonin (MT) (N-acetyl-5-methoxytryptamine) is an indoleamine recognized primarily for its crucial role in regulating sleep through circadian rhythm modulation in humans and animals. Beyond its association with the pineal gland, it is synthesized in various tissues, functioning as a hormone, tissue factor, autocoid, paracoid, and antioxidant, impacting multiple organ systems, including the gut-brain axis. However, the mechanisms of ...Review Article -
The lives of cells, recorded
(2024)Nature Reviews GeneticsA paradigm for biology is emerging in which cells can be genetically programmed to write their histories into their own genomes. These records can subsequently be read, and the cellular histories reconstructed, which for each cell could include a record of its lineage relationships, extrinsic influences, internal states and physical locations, over time. DNA recording has the potential to transform the way that we study developmental and ...Review Article -
Opening the species box: what parsimonious microscopic models of speciation have to say about macroevolution
(2024)Journal of Evolutionary BiologyIn the last two decades, lineage-based models of diversification, where species are viewed as particles that can divide (speciate) or die (become extinct) at rates depending on some evolving trait, have been very popular tools to study macroevolutionary processes. Here, we argue that this approach cannot be used to break down the inner workings of species diversification and that "opening the species box" is necessary to understand the ...Review Article -
Roadmap on methods and software for electronic structure based simulations in chemistry and materials
(2024)Electronic StructureThis Roadmap article provides a succinct, comprehensive overview of the state of electronic structure (ES) methods and software for molecular and materials simulations. Seventeen distinct sections collect insights by 51 leading scientists in the field. Each contribution addresses the status of a particular area, as well as current challenges and anticipated future advances, with a particular eye towards software related aspects and providing ...Review Article -
Applications and future developments of the (thermo-) poro-elastic theory in geophysics
(2025)Earth-Science ReviewsFluids are naturally present in the crust from subsoil to several kilometers deep. The representation of the Earth's crust as a purely elastic medium ignores the effects of fluids within rock pores. Because the presence of fluids alters the mechanical response of rocks, the theory of poro-elasticity can be used to more accurately represent the deformation and the stress field of the crust, especially when the fluid saturation of rocks is ...Review Article -
Reactivity Inside Molecular Flasks: Acceleration Modes and Types of Selectivity Obtainable
(2024)Angewandte Chemie. International EditionThere is increasing interest in the discovery and application of molecular flasks-supramolecular host structures capable of catalyzing organic reactions. Reminiscent of enzymes due to possessing a host cavity akin to an active site, molecular flasks can exhibit complex catalytic mechanisms and in many cases provide selectivity not achievable in bulk solvent. In this Review, we aim to organize the increasingly diverse examples through a ...Review Article -
Cyclization by Intramolecular Suzuki-Miyaura Cross-Coupling-A Review
(2024)Chemistry - A European JournalRing systems of all sizes are frequent core or substructures in natural products and they are important elements of many drug molecules, as they often confer high binding affinity to and selectivity for disease-relevant biological targets. A uniform key transformation in the synthesis of such structures is the cyclization step. Among the various approaches that have been developed for ring closure, the intramolecular Suzuki-Miyaura reaction ...Review Article -
Scene Representations for Robotic Spatial Perception
(2025)Annual Review of Control, Robotics, and Autonomous SystemsThe ability of a robot to build a persistent, accurate, and actionable model of its surroundings through sensor data in a timely manner is crucial for autonomous operation. While representing the world as a point cloud might be sufficient for localization, denser scene representations are required for obstacle avoidance. On the other hand, higher-level semantic information is often crucial for breaking down the necessary steps to autonomously ...Review Article