Recent Submissions 

  1. “Quantifying the implications of behavioral changes induced by digitalization on energy transition: A systematic review of methodological approaches” 

    Stermieri L.; Kober T.; Schmidt T.J.; et al. (2023)
    Energy Research and Social Science
    Digitalization is expected to play an important role in mitigating environmental issues and supporting the energy transition to meet future energy and climate targets. To understand the role of Information and Communication Technology (ICT) applications in the energy transition, a prior understanding of their implications on user behavior and energy consumption is essential to identify and prevent potential rebound effects. With a systematic ...
    Review Article
  2. Phase Separation in Biology and Disease; Current Perspectives and Open Questions 

    Boeynaems S.; Chong S.; Gsponer J.; et al. (2023)
    Journal of Molecular Biology
    In the past almost 15 years, we witnessed the birth of a new scientific field focused on the existence, formation, biological functions, and disease associations of membraneless bodies in cells, now referred to as biomolecular condensates. Pioneering studies from several laboratories [reviewed in1–3] supported a model wherein biomolecular condensates associated with diverse biological processes form through the process of phase separation. ...
    Review Article
  3. Cenozoic exhumation in the Mediterranean and the Middle East 

    Lanari, Riccardo; Boutoux, Alex; Faccenna, Claudio; et al. (2023)
    Earth-Science Reviews
    We investigate the processes driving spatial-temporal patterns of Cenozoic exhumation in the Mediterranean and the Middle East by compiling >7300 published low-temperature thermochronometric ages and converting them into exhumation rates through a formal inversion process based on thermal modeling and closure temperature kinetics. Exhumation rates are resolved using piecewise-continuous spatial variability and timesteps of five million ...
    Review Article
  4. Electrochemical-based approaches for the treatment of forever chemicals: Removal of perfluoroalkyl and polyfluoroalkyl substances (PFAS) from wastewater 

    Sivagami K.; Sharma P.; Karim A.V.; et al. (2023)
    Science of The Total Environment
    Electrochemical based approaches for the treatment of recalcitrant water borne pollutants are known to exhibit superior function in terms of efficiency and rate of treatment. Considering the stability of Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are designated as forever chemicals, which generating from various industrial activities. PFAS are contaminating the environment in small concentrations, yet exhibit severe environmental ...
    Review Article
  5. Engineering ribosomally synthesized and posttranslationally modified peptides as new antibiotics 

    Vagstad, Anna L. (2023)
    Current Opinion in Biotechnology
    The rise of antimicrobial resistance is an urgent public health threat demanding the invention of new drugs to combat infections. Naturally sourced nonribosomal peptides (NRPs) have a long history as antimicrobial drugs. Through recent advances in genome mining and engineering technologies, their ribosomally synthesized and posttranslationally modified peptide (RiPP) counterparts are poised to further contribute to the arsenal of ...
    Review Article
  6. State of Knowledge on the Acquisition, Diversity, Interspecies Attribution and Spread of Antimicrobial Resistance between Humans, Animals and the Environment: A Systematic Review 

    Meier H.; Spinner K.; Crump L.; et al. (2023)
    Resistance to antibiotics is considered one of the most urgent global public health concerns. It has considerable impacts on health and the economy, being responsible for the failure to treat infectious diseases, higher morbidity and mortality rates, and rising health costs. In spite of the joint research efforts between different humans, animals and the environment, the key directions and dynamics of the spread of antimicrobial resistance ...
    Review Article
  7. The global depth range of marine fishes and their genetic coverage for environmental DNA metabarcoding 

    Duhamet, Agnes; Albouy, Camille; Marques, Virginie; et al. (2023)
    Ecology and Evolution
    The bathymetric and geographical distribution of marine species represent a key information in biodiversity conservation. Yet, deep-sea ecosystems are among the least explored on Earth and are increasingly impacted by human activities. Environmental DNA (eDNA) metabarcoding has emerged as a promising method to study fish biodiversity but applications to the deep-sea are still scarce. A major limitation in the application of eDNA metabarcoding ...
    Review Article
  8. Concurrent deficit and surplus situations in the future renewable Swiss and European electricity system 

    Lienhard N.; Mutschler R.; Leenders L.; et al. (2023)
    Energy Strategy Reviews
    European countries aim to achieve net zero CO2 emissions by mid-century. Consequently, the European energy system and particularly the electricity system must undergo major changes. An increasing electrification of the mobility and heating sector is required for decarbonisation, which reserves electricity a central role on the path towards net zero CO2 emissions. However, to meet emission targets, the electricity supply must originate ...
    Review Article
  9. Potential Synergistic Supplementation of NAD+ Promoting Compounds as a Strategy for Increasing Healthspan 

    Sharma A.; Chabloz S.; Lapides R.A.; et al. (2023)
    Disrupted biological function, manifesting through the hallmarks of aging, poses one of the largest threats to healthspan and risk of disease development, such as metabolic disorders, cardiovascular ailments, and neurodegeneration. In recent years, numerous geroprotectors, senolytics, and other nutraceuticals have emerged as potential disruptors of aging and may be viable interventions in the immediate state of human longevity science. ...
    Review Article
  10. Promoting the construction of intelligent knowledge with the help of various methods of cognitively activating instruction 

    Schumacher, Ralph; Stern, Elsbeth (2023)
    Frontiers in Education
    How can we promote the construction of intelligent knowledge that facilitates the transfer of knowledge to new situations? This article gives an overview of the current state of empirical research on methods of cognitively activating teaching that promote conceptual change and flexible application of knowledge in new situations. “Cognitively activating” means that these methods promote the active construction of knowledge by facilitating ...
    Review Article
  11. In vitro human gut microbiota fermentation models: opportunities, challenges, and pitfalls 

    Isenring, Julia; Bircher, Lea; Geirnaert, Annelies; et al. (2023)
    Microbiome Research Reports
    The human gut microbiota (HGM) plays a pivotal role in health and disease. Consequently, nutritional and medical research focusing on HGM modulation strategies as a means of improving host health is steadily increasing. In vitro HGM fermentation models offer a valid complement to human and animal studies when it comes to the mechanistic exploration of novel modulation approaches and their direct effects on HGM composition and activity, ...
    Review Article
  12. Missing Link: Strategies of a Viennese Architeture Group (1790-1890) - Review 

    Wegerhoff, Erik (2022)
    Drawing Matter
    Review Article
  13. Trends and variability in the ocean carbon sink 

    Gruber, Nicolas; Bakker, Dorothee C.E.; DeVries, Tim; et al. (2023)
    Nature Reviews Earth & Environment
    The ocean has absorbed 25 ± 2% of the total anthropogenic CO2 emissions from the early 1960s to the late 2010s, with rates more than tripling over this period and with a mean uptake of –2.7 ± 0.3 Pg C year–1 for the period 1990 through 2019. This growth of the ocean sink matches expectations based on the increase in atmospheric CO2, but research has shown that the sink is more variable than long assumed. In this Review, we discuss trends ...
    Review Article
  14. Prospects of coupled iron-based nanostructures in preclinical antibacterial therapy 

    Han, Jingjing; Zeng, Shuang; Chen, Yahui; et al. (2023)
    Advanced Drug Delivery Reviews
    Bacterial infections can threaten human health. Drug-resistant bacteria have become a challenge because of the excessive use of drugs. We summarize the current metallic antibacterial materials, especially Fe-based materials, for efficiently killing bacteria. The possible antibacterial mechanisms of metallic antibacterial agents are classified into interactions with bacterial proteins, iron metabolism, catalytic activity, and combinations ...
    Review Article
  15. Does chronic use of amphetamine-type stimulants impair interference control? – A meta-analysis 

    Opitz A.; Petasch M.S.; Klappauf R.; et al. (2023)
    Neuroscience and Biobehavioral Reviews
    In substance use and addiction, inhibitory control is key to ignoring triggers, withstanding craving and maintaining abstinence. In amphetamine-type stimulant (ATS) users, most research focused on behavioral inhibition, but largely neglected the equally important subdomain of cognitive interference control. Given its crucial role in managing consumption, we investigated the relationship between interference control and chronic ATS use in ...
    Review Article
  16. Barbara Bonhage: Gnadenlos geirrt. Die Geschichte meiner Grossmutter 1907-1945 

    Spuhler, Gregor (2022)
    Review Article
  17. Prognostic and therapeutic potential of microRNAs for fracture healing processes and non-union fractures: A systematic review 

    Breulmann, Franziska Lioba; Hatt, Luan Phelipe; Schmitz, Boris; et al. (2023)
    Clinical and Translational Medicine
    Background: Approximately 10% of all bone fractures result in delayed fracture healing or non-union; thus, the identification of biomarkers and prognostic factors is of great clinical interest. MicroRNAs (miRNAs) are known to be involved in the regulation of the bone healing process and may serve as functional markers for fracture healing. Aims and methods: This systematic review aimed to identify common miRNAs involved in fracture healing ...
    Review Article
  18. Editing a gateway for cell therapy across the blood-brain barrier 

    Buil, Beatriz Achon; Tackenberg, Christian; Rust, Ruslan (2022)
    Brain: A Journal of Neurology
    Stem cell therapy has been shown to improve stroke outcomes in animal models and is currently advancing towards clinical practice. However, uncertainty remains regarding the optimal route for cell delivery to the injured brain. Local intracerebral injections are effective in precisely delivering cells into the stroke cavity but carry the risk of damaging adjacent healthy tissue. Systemic endovascular injections, meanwhile, are minimally ...
    Review Article
  19. Environmental controls on very high δ<sup>238</sup>U values in reducing sediments: Implications for Neoproterozoic seawater records 

    Clarkson M.O.; Sweere T.C.; Chiu C.F.; et al. (2023)
    Earth-Science Reviews
    Uranium isotopes (δ238U) are a widely applied tool for tracing global changes in oceanic anoxia. Interpretation of seawater values and trends, often reconstructed from carbonates, requires knowledge of the U isotope fractionation that occurs during U reduction, typically favouring the heavier 238U isotope relative to 235U. Yet the environmental controls on the expression of isotope enrichment during reduction (Δ238Uanox) are poorly ...
    Review Article
  20. On the Sensitivity of Trade Costs to Services-trade Restrictions 

    Egger, Peter H.; Blank, Sven (2022)
    The World Economy
    Review Article

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