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Structure and characterization of a novel chicken biotin-binding protein A (BBP-A)
(2007)BMC Structural BiologyBackground The chicken genome contains a BBP-A gene showing similar characteristics to avidin family genes. In a previous study we reported that the BBP-A gene may encode a biotin-binding protein due to the high sequence similarity with chicken avidin, especially at regions encoding residues known to be located at the ligand-binding site of avidin. Results Here, we expand the repertoire of known macromolecular biotin binders by ...Journal Article -
Avidin related protein 2 shows unique structural and functional features among the avidin protein family
(2005)BMC BiotechnologyBackground The chicken avidin gene family consists of avidin and several avidin related genes (AVRs). Of these gene products, avidin is the best characterized and is known for its extremely high affinity for D-biotin, a property that is utilized in numerous modern life science applications. Recently, the AVR genes have been expressed as recombinant proteins, which have shown different biotin-binding properties as compared to avidin. ...Journal Article -
Internalization of novel non-viral vector TAT-streptavidin into human cells
(2007)BMC BiotechnologyJournal Article -
Chicken genome analysis reveals novel genes encoding biotin-binding proteins related to avidin family
(2005)BMC GenomicsBackground A chicken egg contains several biotin-binding proteins (BBPs), whose complete DNA and amino acid sequences are not known. In order to identify and characterise these genes and proteins we studied chicken cDNAs and genes available in the NCBI database and chicken genome database using the reported N-terminal amino acid sequences of chicken egg-yolk BBPs as search strings. Results Two separate hits showing significant homology ...Journal Article