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Historical and contemporary cultural ecosystem service values in the rapidly urbanizing city state of Singapore
(2015)AmbioJournal Article -
H. pylori-Induced DNA Strand Breaks Are Introduced by Nucleotide Excision Repair Endonucleases and Promote NF-kappaB Target Gene Expression
(2015)Cell ReportsThe human bacterial pathogen Helicobacter pylori exhibits genotoxic properties that promote gastric carcinogenesis. H. pylori introduces DNA double strand breaks (DSBs) in epithelial cells that trigger host cell DNA repair efforts. Here, we show that H. pylori-induced DSBs are repaired via error-prone, potentially mutagenic non-homologous end-joining. A genome-wide screen for factors contributing to DSB induction revealed a critical role ...Journal Article -
A Robust and Informative Method for Solving Large-Scale Power Flow Problems
(2015)Computational optimization and applicationsJournal Article -
Differential genetic interactions of yeast stress response MAPK pathways
(2015)Molecular Systems BiologyGenetic interaction screens have been applied with great success in several organisms to study gene function and the genetic architecture of the cell. However, most studies have been performed under optimal growth conditions even though many functional interactions are known to occur under specific cellular conditions. In this study, we have performed a large-scale genetic interaction analysis in Saccharomyces cerevisiae involving ...Journal Article -
Site amplification, attenuation, and scattering from noise correlation amplitudes across a dense array in Long Beach, CA
(2015)Geophysical Research LettersJournal Article -
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Geometrical influence on vortex shedding in turbulent axisymmetric wakes
(2015)Physics of FluidsJournal Article -
A PIV measurement of the natural transition of a natural convection boundary layer
(2015)Experiments in FluidsA natural convection boundary layer undergoing natural transition to turbulence is investigated by particle image velocimetry (PIV) measurements for the first time. The boundary layer adjacent to an isothermally heated plate immersed in water is subjected to environmental noise, the transition of which is therefore regarded as a natural transition. Distinct stripe-like flow structures characterising the natural transition of the natural ...Journal Article -
Single Geographic Origin of a Widespread Autotetraploid Arabidopsis arenosa Lineage Followed by Interploidy Admixture
(2015)Molecular Biology and EvolutionWhole-genome duplication, which leads to polyploidy, has been implicated in speciation and biological novelty. In plants, many species exhibit ploidy variation, which is likely representative of an early stage in the evolution of polyploid lineages. To understand the evolution of such multiploidy systems, we must address questions such as whether polyploid lineage(s) had a single or multiple origins, whether admixture occurs between ...Journal Article -
Sources and contributions of wood smoke during winter in London: assessing local and regional influences
(2015)Atmospheric Chemistry and PhysicsDetermining the contribution of wood smoke to air pollution in large cities such as London is becoming increasingly important due to the changing nature of domestic heating in urban areas. During winter, biomass burning emissions have been identified as a major cause of exceedances of European air quality limits. The aim of this work was to quantify the contribution of biomass burning in London to concentrations of PM2.5 and determine ...Journal Article