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Crystal structure of 2-[6-(2-formylphenoxy)-2,4-hexadiynyloxy]-benzaldehyde,C20H14O4
(2006)Zeitschrift für Kristallographie. New Crystal StructuresJournal Article -
Integración por cuantificación de sistemas stiff
(2007)Revista iberoamericana de automática e informática industrialEste artículo presenta un nuevo método de integración numérica de ecuaciones diferenciales ordinarias basado en la cuantificación de las variables de estado. Utilizando conceptos de integración implícita, el nuevo método denominado BQSS (Backward Quantized State Systems) permite integrar sistemas stiff de manera eficiente. Siendo el primer método de cuantificación para sistemas stiff, BQSS es en sí un método explícito, por lo que la ...Journal Article -
Long-term Biomonitoring of Alpine Waters in the Swiss National Park
(2009)eco.mont: Journal on Protected Mountain Areas Research and ManagementThis paper summarizes the initial results from the long-term monitoring program of running and standing waters in a high elevation cirque landscape (Macun Lakes) in the Swiss National Park. The region comprises two contrasting basins with different water sources, a glacier-fed basin and a precipitation-fed basin. Monitoring encompasses annual measures of physico-chemistry of the waters along with samples of macroinvertebrates in midsummer. ...Journal Article -
Systematic evaluation of objective functions for predicting intracellular fluxes in Escherichia coli
(2007)Molecular Systems BiologyTo which extent can optimality principles describe the operation of metabolic networks? By explicitly considering experimental errors and in silico alternate optima in flux balance analysis, we systematically evaluate the capacity of 11 objective functions combined with eight adjustable constraints to predict 13C‐determined in vivo fluxes in Escherichia coli under six environmental conditions. While no single objective describes the flux ...Journal Article -
Parasites lead to evolution of robustness against gene loss in host signaling networks
(2008)Molecular Systems BiologyMany biological networks can maintain their function against single gene loss. However, the evolutionary mechanisms responsible for such robustness remain unclear. Here, we demonstrate that antagonistic host–parasite interactions can act as a selective pressure driving the emergence of robustness against gene loss. Using a model of host signaling networks and simulating their coevolution with parasites that interfere with network function, ...Journal Article -
PhosphoPep—a phosphoproteome resource for systems biology research in Drosophila Kc167 cells
(2007)Molecular Systems BiologyThe ability to analyze and understand the mechanisms by which cells process information is a key question of systems biology research. Such mechanisms critically depend on reversible phosphorylation of cellular proteins, a process that is catalyzed by protein kinases and phosphatases. Here, we present PhosphoPep, a database containing more than 10 000 unique high‐confidence phosphorylation sites mapping to nearly 3500 gene models and 4600 ...Journal Article -
Braucht die Schweiz Nationallinzenzen?
(2007)GMS Medizin, Bibliothek, InformationJournal Article -
Hf–W thermochronometry: Closure temperature and constraints on the accretion and cooling history of the H chondrite parent body
(2008)Earth and Planetary Science LettersJournal Article -
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The Application of Robust Regression to a Production Function Comparison
(2008)The Open Agriculture JournalThe adequate representation of crop response functions is crucial for agronomic as well as agricultural economic modeling and analysis. So far, the evaluation of such functions focused on the comparison of different functional forms. In this article, the perspective is expanded also by considering different regression methods. This is motivated by the fact that exceptional crop yield observations (outliers) can cause misleading results ...Journal Article