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Robustness analysis of a green chemistry-based model for the classification of silver nanoparticles synthesis processes
(2017)Journal of Cleaner ProductionThis paper proposes a robustness analysis based on Multiple Criteria Decision Aiding (MCDA). The ensuing model was used to assess the implementation of green chemistry principles in the synthesis of silver nanoparticles. Its recommendations were also compared to an earlier developed model for the same purpose to investigate concordance between the models and potential decision support synergies. A three-phase procedure was adopted to ...Journal Article -
Effects of N-glycosylation of the human cation channel TRPA1 on agonist-sensitivity
(2016)Bioscience ReportsDetermining the functional significance of post-translational modifications advances our understanding of many broadly-expressed proteins, and particularly ion channels. The enzymes that catalyse these modifications are often expressed in a cell-type specific manner, resulting in considerable structural diversity among post-translationally modified proteins that are expressed across a variety of cell types. TRP channels exhibit notably ...Journal Article -
Modelling economic losses of historic and present-day high-impact winter windstorms in Switzerland
(2016)Tellus A: Dynamic Meteorology and OceanographyJournal Article -
Using a direct simulation Monte Carlo approach to model collisions in a buffer gas cell
(2017)The Journal of Chemical PhysicsA direct simulation Monte Carlo (DSMC) method is applied to model collisions between He buffer gas atoms and ammonia molecules within a buffer gas cell. State-to-state cross sections, calculated as a function of the collision energy, enable the inelastic collisions between He and NH3 to be considered explicitly. The inclusion of rotational-state-changing collisions affects the translational temperature of the beam, indicating that elastic ...Journal Article -
A Methodologic Approach for the Selection of Bio-Resorbable Polymers in the Development of Medical Devices: The Case of Poly(l-lactide-co-ε-caprolactone)
(2018)PolymersIn the last decades bioresorbable and biodegradable polymers have gained a very good reputation both in research and in industry thanks to their unique characteristics. They are able to ensure high performance and biocompatibility, at the same time avoiding post-healing surgical interventions for device removal. In the medical device industry, it is widely known that product formulation and manufacturing need to follow specific procedures ...Journal Article -
Postcollisional cooling history of the Eastern and Southern Alps and its linkage to Adria indentation
(2017)International Journal of Earth SciencesIndentation of rigid blocks into rheologically weak orogens is generally associated with spatiotemporally variable vertical and lateral block extrusion. The European Eastern and Southern Alps are a prime example of microplate indentation, where most of the deformation was accommodated north of the crustal indenter within the Tauern Window. However, outside of this window only the broad late-stage exhumation pattern of the indented units ...Journal Article -
The Evolution of Orphan Regions in Genomes of a Fungal Pathogen of Wheat
(2016)mBioFungal plant pathogens rapidly evolve virulence on resistant hosts through mutations in genes encoding proteins that modulate the host immune responses. The mutational spectrum likely includes chromosomal rearrangements responsible for gains or losses of entire genes. However, the mechanisms creating adaptive structural variation in fungal pathogen populations are poorly understood. We used complete genome assemblies to quantify structural ...Journal Article -
Detection of H alpha emission from PZ Telescopii B using SPHERE/ZIMPOL
(2019)Astronomy & AstrophysicsHα is a powerful tracer of accretion and chromospheric activity, which has been detected in the case of young brown dwarfs and even recently in planetary mass companions (e.g. PDS70 b and c). Hα detections and characterisation of brown dwarf and planet companions can further our knowledge of their formation and evolution, and expanding such a sample is therefore our primary goal. We used the Zurich Imaging POLarimeter (ZIMPOL) of the ...Journal Article -
Rapid and sustained homeostatic control of presynaptic exocytosis at a central synapse
(2019)Proceedings of the National Academy of Sciences of the United States of AmericaAnimal behavior is remarkably robust despite constant changes in neural activity. Homeostatic plasticity stabilizes central nervous system (CNS) function on time scales of hours to days. If and how CNS function is stabilized on more rapid time scales remains unknown. Here, we discovered that mossy fiber synapses in the mouse cerebellum homeostatically control synaptic efficacy within minutes after pharmacological glutamate receptor ...Journal Article -
Studies of dijet transverse momentum balance and pseudorapidity distributions in pPb collisions at √sNN = 5.02 TeV
(2014)The European Physical Journal CDijet production has been measured in pPb collisions at a nucleon–nucleon centre-of-mass energy of 5.02TeV. A data sample corresponding to an integrated luminosity of 35 nb−1 was collected using the Compact Muon Solenoid detector at the Large Hadron Collider. The dijet transverse momentum balance, azimuthal angle correlations, and pseudorapidity distributions are studied as a function of the transverse energy in the forward calorimeters ...Journal Article