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Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
(2006)BMC BioinformaticsBackground The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of two sequences is closer to a third one. The most accurate method is currently maximum likelihood over the entire triplet. However, this approach is relatively time consuming. Results We show that an alternative estimator, based on pairwise estimates and therefore ...Journal Article