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Plant diversity moderates drought stress in grasslands: Implications from a large real-world study on 13C natural abundances
(2016)Science of The Total EnvironmentLand-use change and intensification play a key role in the current biodiversity crisis. The resulting species loss can have severe effects on ecosystem functions and services, thereby increasing ecosystem vulnerability to climate change. We explored whether land-use intensification (i.e. fertilization intensity), plant diversity and other potentially confounding environmental factors may be significantly related to water use (i.e. drought ...Journal Article -
Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells
(2016)Cell Reports ~ Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem CellsReprogramming of somatic cells to induced pluripotent stem cells (iPSCs) is typically an inefficient and asynchronous process. A variety of technological efforts have been made to accelerate and/or synchronize this process. To define a unified framework to study and compare the dynamics of reprogramming under different conditions, we developed an in silico analysis platform based on mathematical modeling. Our approach takes into account ...Journal Article -
Discovery and Function of a General Core Hormetic Stress Response in E. coli Induced by Sublethal Concentrations of Antibiotics
(2016)Cell ReportsA better understanding of the impact of antibiotics on bacteria is required to increase the efficiency of antibiotic treatments and to slow the emergence of resistance. Using Escherichia coli, we examined how bacteria exposed to sublethal concentrations of ampicillin adjust gene expression patterns and metabolism to simultaneously deal with the antibiotic-induced damage and maintain rapid growth. We found that the treated cells increased ...Journal Article -
Nitrogen-Based Fuels: A Power-to-Fuel-to-Power Analysis
(2016)Angewandte ChemieWhat are the fuels of the future? Seven representative carbon‐ and nitrogen‐based fuels are evaluated on an energy basis in a power‐to‐fuel‐to‐power analysis as possible future chemical hydrogen‐storage media. It is intriguing to consider that a nitrogen economy, where hydrogen obtained from water splitting is chemically stored on abundant nitrogen in the form of a nontoxic and safe nitrogen‐based alternative fuel, is energetically feasible.Journal Article -
Estimating the effective elastic modulus and specific fracture energy of snowpack layers from field experiments
(2016)Journal of GlaciologyMeasurements of the mechanical properties of snow are essential for improving our understanding and the prediction of snow failure and hence avalanche release. We performed fracture mechanical experiments in which a crack was initiated by a saw in a weak snow layer underlying cohesive snow slab layers. Using particle tracking velocimetry (PTV), the displacement field of the slab was determined and used to derive the mechanical energy of ...Journal Article -
Unraveling the optomechanical nature of plasmonic trapping
(2016)Light: Science & ApplicationsNoninvasive and ultra-accurate optical manipulation of nanometer objects has recently gained interest as a powerful tool in nanotechnology and biophysics. Self-induced back-action (SIBA) trapping in nano-optical cavities has the unique potential for trapping and manipulating nanometer-sized objects under low optical intensities. However, thus far, the existence of the SIBA effect has been shown only indirectly via its enhanced trapping ...Journal Article