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Fabrication of Single and Multi-Layer Fibrous Biomaterial Scaffolds for Tissue Engineering
(2009)Proceedings of the ASME 2008 International Mechanical Engineering Congress and ExpositionFor regenerative medicine applications, we need to expand our understanding of the mechanisms by which nature assembles and functionalizes specialized complex tissues to form a complete organism. The first step towards this goal involves understanding the underlying complex mechanisms of highly organized behavior spanning not only diverse scientific fields, but also nano, micro and macro length-scales. For example, an engineered fibrous ...Conference Paper -
Dry Spinning Polymeric Nano/microfiber Arrays using Glass Micropipettes with Controlled Porosities and Fiber Diameters
(2007)Proceedings of the 7th IEEE International Conference on NanotechnologyWe present a method for dry spinning polymeric nano/microfiber arrays. In this technique polymer solution is continuously ejected from a stationary glass micropipette and the fibers are deposited as continuous arrays in parallel and complex geometrical configurations on a rotating substrate mounted on to a translation stage. As the polymer solution exits the glass micropipette, ambient air is used to evaporate the solvent, thus solidifying ...Conference Paper -
Polymeric Micro/Nanofiber Manufacturing and Mechanical Characterization
(2009)ASME 2008 International Mechanical Engineering Congress and ExpositionPolymeric nanofibers are finding increasing number of applications and hold the potential to revolutionize diverse fields such as tissue engineering, smart textiles, sensors, and actuators. Aligning and producing long smooth, uniform and defect-free fibers with control on fiber dimensions at the submicron and nanoscale has been challenging due to fragility of polymeric materials. Besides fabrication, the other challenge lies in the ability ...Conference Paper