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Impact of the tree prior on estimating clock rates during epidemic outbreaks
(2018)Proceedings of the National Academy of Sciences of the United States of AmericaBayesian phylogenetics aims at estimating phylogenetic trees together with evolutionary and population dynamic parameters based on genetic sequences. It has been noted that the clock rate, one of the evolutionary parameters, decreases with an increase in the sampling period of sequences. In particular, clock rates of epidemic outbreaks are often estimated to be higher compared with the long-term clock rate. Purifying selection has been ...Journal Article -
Phylogenetic classification of the world's tropical forests
(2018)Proceedings of the National Academy of Sciences of the United States of AmericaKnowledge about the biogeographic affinities of the world’s tropical forests helps to better understand regional differences in forest structure, diversity, composition, and dynamics. Such understanding will enable anticipation of region-specific responses to global environmental change. Modern phylogenies, in combination with broad coverage of species inventory data, now allow for global biogeographic analyses that take species evolutionary ...Journal Article -
Rotational 3D printing of damage-tolerant composites with programmable mechanics
(2018)Proceedings of the National Academy of Sciences of the United States of AmericaNatural composites exhibit exceptional mechanical performance that often arises from complex fiber arrangements within continuous matrices. Inspired by these natural systems, we developed a rotational 3D printing method that enables spatially controlled orientation of short fibers in polymer matrices solely by varying the nozzle rotation speed relative to the printing speed. Using this method, we fabricated carbon fiber–epoxy composites ...Journal Article -
Extratropical Atmospheric Predictability From the Quasi-Biennial Oscillation in Subseasonal Forecast Models
(2018)Journal of Geophysical Research: AtmospheresThe effect of the Quasi‐Biennial Oscillation (QBO) on the Northern Hemisphere wintertime stratospheric polar vortex is evaluated in five operational subseasonal forecasting models. Of these five models, the three with the best stratospheric resolution all indicate a weakened vortex during the easterly phase of the QBO relative to its westerly phase, consistent with the Holton‐Tan effect. The magnitude of this effect is well captured for ...Journal Article -
Improved Teleconnection-Based Dynamical Seasonal Predictions of Boreal Winter
(2018)Geophysical Research LettersClimate and weather variability in the North Atlantic region is determined largely by the North Atlantic Oscillation (NAO). The potential for skillful seasonal forecasts of the winter NAO using an ensemble‐based dynamical prediction system has only recently been demonstrated. Here we show that the winter predictability can be significantly improved by refining a dynamical ensemble through subsampling. We enhance prediction skill of surface ...Journal Article -
Analysis of Inorganic Nanoparticles by Single-particle Inductively Coupled Plasma Time-of-Flight Mass Spectrometry
(2018)ChimiaDue to the rapid development of nanotechnologies, engineered nanomaterials (ENMs) and nanoparticles (ENPs) are becoming a part of everyday life: nanotechnologies are quickly migrating from laboratory benches to store shelves and industrial processes. As the use of ENPs continues to expand, their release into the environment is unavoidable; however, understanding the mechanisms and degree of ENP release is only possible through direct ...Journal Article -
Nickel and its isotopes in organic-rich sediments: implications for oceanic budgets and a potential record of ancient seawater
(2018)Earth and Planetary Science LettersJournal Article -
Induction of Intracellular Reductive Stress with a Photoactivatable Phosphine Probe
(2018)ChimiaReductive stress is a condition present in cells that have an increased concentration of reducing species, and it has been associated with a number of pathologies, such as neurodegenerative diseases and cancer. The tools available to study reductive stress lack both in selectivity and specific targeting and some of these shortcomings can be addressed by using photoactivatable compounds. We developed a photoactivatable phosphonium probe, ...Journal Article -
The in silico human surfaceome
(2018)Proceedings of the National Academy of Sciences of the United States of AmericaCell-surface proteins are of great biomedical importance, as demonstrated by the fact that 66% of approved human drugs listed in the DrugBank database target a cell-surface protein. Despite this biomedical relevance, there has been no comprehensive assessment of the human surfaceome, and only a fraction of the predicted 5,000 human transmembrane proteins have been shown to be located at the plasma membrane. To enable analysis of the human ...Journal Article -
Effect of environmental conditions on sun-induced fluorescence in a mixed forest and a cropland
(2018)Remote Sensing of EnvironmentJournal Article