Genetically Encoded Activators of Small Molecules for Imaging and Drug Delivery
Open access
Datum
2020-05-11Typ
- Review Article
Abstract
Chemical biologists have developed many tools based on genetically encoded macromolecules and small, synthetic compounds. The two different approaches are extremely useful, but they have inherent limitations. In this Minireview, we highlight examples of strategies that combine both concepts to tackle challenging problems in chemical biology. We discuss applications in imaging, with a focus on super‐resolved techniques, and in probe and drug delivery. We propose future directions in this field, hoping to inspire chemical biologists to develop new combinations of synthetic and genetically encoded probes. Mehr anzeigen
Persistenter Link
https://doi.org/10.3929/ethz-b-000404712Publikationsstatus
publishedExterne Links
Zeitschrift / Serie
Angewandte Chemie. International EditionBand
Seiten / Artikelnummer
Verlag
WileyThema
Bioorthogonal labeling; Biosensors; Drug delivery; Fluorescent probes; Genetically encoded tagsFörderung
165551 - Development of Intracellular Photoactivatable Probes (SNF)